Researchers reported fewer BV recurrences over 6 months.
Russo 2019, Benef Microbes · Source
Lactobacillus acidophilus
Strain UALa-01 (UAS Labs)
One of the best-known friendly bacteria, found in the gut and in many yogurts, and studied in women's vaginal and gut health.
Classicone of the best-known probiotic species
48women in a trial of a related strain after BV treatment
10strains in the Daily Probiotic blend
Why we love it
L. acidophilus is a classic gut lactobacillus with a long history of use in foods. We included it as a foundation of the blend alongside the species more typical of the vagina.
What does the research show?
Bacterial vaginosis
In a trial of 48 women with BV, all took a standard antibiotic and then an oral mix of L. acidophilus La-14, L. rhamnosus HN001 and lactoferrin, or a placebo, for six months. The researchers reported fewer BV recurrences with the mix.
Yeast infections
A similar trial of 48 women with recurring yeast infections used the same oral mix after an antifungal cream and reported fewer recurrences than placebo. An older study of 13 women who ate yogurt with L. acidophilus daily reported about three times fewer yeast infections during the yogurt months.
Getting to the vagina after oral use
In healthy women, researchers found L. acidophilus La-14 and L. rhamnosus HN001 in vaginal samples after two weeks of oral capsules.
Gut
In 60 adults with bowel symptoms, L. acidophilus NCFM with Bifidobacterium lactis Bi-07 was linked to less bloating than placebo. In 255 hospital patients on antibiotics, capsules of L. acidophilus CL1285 and L. casei LBC80R were linked to less antibiotic-related diarrhea.
Studies
Human study tested in people Lab study a starting point, not proof
Studies on other strains of this species
Researchers reported fewer recurrences over 6 months.
Russo 2019, Mycoses · Source
Nugent scores returned to normal more often than with placebo.
Russo 2018, Arch Gynecol Obstet · Source
Both strains were found in vaginal samples, lasting at least a week after the last dose.
De Alberti 2015, Arch Gynecol Obstet · Source
About three times fewer yeast infections during the yogurt months.
Hilton 1992, Ann Intern Med · Source
Antibiotic-related diarrhea in 16% (higher dose) and 28% (lower dose) vs 44% on placebo.
Gao 2010, Am J Gastroenterol · Source
Bloating score improved more than with placebo at 8 weeks. The main overall-relief measures were not clearly different.
Ringel 2011, J Clin Gastroenterol · Source
Which strain do we use?
Our strain is L. acidophilus UALa-01 (UAS Labs). The studies above used other strains of this species, and results belong to the strain tested.
Is L. acidophilus safe to take?
Side effects in the gut trials above were similar to placebo. Rare cases of serious Lactobacillus bloodstream and heart-valve infections have been reported, for example in a person with an artificial heart valve. If you are immunocompromised, have a central line or an artificial heart valve, are critically ill, or are pregnant or breastfeeding, ask your clinician before taking any probiotic.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Last reviewed: November 2026.
Found in
Related ingredients
Reviewed by the Momotaro Apotheca medical team, including OB-GYNs and naturopathic doctors. Educational information, not medical advice. All ingredient research