Lactobacillus gasseri

Strain UALg-05 (UAS Labs)

A lactobacillus that lives naturally in the vagina, mouth and gut, and is often part of the lactobacilli researchers find in a healthy vagina.

Nativeto the vagina, mouth and gut
100women in a vaginal-capsule trial with a related strain
10strains in the Daily Probiotic blend

Why we love it

L. gasseri is one of the lactobacilli that researchers commonly find in a healthy vagina, and it also lives in the gut. We included it so the blend reflects the range of lactobacilli found in both places.

What does the research show?

Bacterial vaginosis

In a trial of 100 women treated for BV, researchers compared a vaginal capsule containing L. gasseri and L. rhamnosus (EcoVag) with a placebo. At 6 months, 65% of the probiotic group and 46% of the placebo group were still free of BV. In another trial of 59 women, adding an oral mix of L. gasseri TM13 and L. crispatus LG55 to standard antibiotic treatment did not improve cure rates.

Yeast infections

In a small open study, women with recurring yeast infections took an antifungal with or without EcoVag vaginal capsules. At 12 months, 89% versus 70% were still clear, a difference that was not statistically significant.

Oral mixes

A review of three small oral trials looked at a four-strain mix that included L. gasseri LbV 150N. Nugent scores, a lab measure of BV, were lower than with placebo.

Studies

Human study tested in people   Lab study a starting point, not proof

Studies on other strains of this species

Human study Randomized, placebo-controlled, 100 women with BV

Strain: EcoVag: L. gasseri + L. rhamnosus, vaginal, after clindamycin

65% vs 46% were BV-free at 6 months.

Larsson 2008, BMC Women's Health · Source

Human study Small open study, 40 women with BV or yeast infections

Strain: EcoVag: L. gasseri + L. rhamnosus, vaginal, with fluconazole

Yeast infections: 89% vs 70% clear at 12 months, not statistically significant.

Pendharkar 2015, BMC Infect Dis · Source

Human study Meta-analysis of 3 trials, 118 women

Strains (oral mix): L. gasseri LbV 150N with L. crispatus, L. jensenii and L. rhamnosus strains

Nugent scores were lower than with placebo. Only 36 of the women had BV.

de Vrese 2019, Benef Microbes · Source

Human study Randomized, controlled, 59 women with BV

Strains (oral mix): L. gasseri TM13 + L. crispatus LG55, with standard antibiotic

No better cure rate than antibiotic alone. Strains were not found in the vagina.

Qi 2023, Front Immunol · Source

Which strain do we use?

Our strain is L. gasseri UALg-05 (UAS Labs). It was also one of 10 strains in a small oral blend study (Martoni 2022), where vaginal pH fell slightly over 28 days. The other studies above used other strains of this species, and results belong to the strain tested.

Is L. gasseri safe to take?

The trials above did not report safety concerns, but most were small. If you are immunocompromised, have a central line, are critically ill, or are pregnant or breastfeeding, ask your clinician before taking any probiotic.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Last reviewed: November 2026.

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Reviewed by the Momotaro Apotheca medical team, including OB-GYNs and naturopathic doctors. Educational information, not medical advice. All ingredient research