Lower belly pain scores and more normal stools than placebo.
Martoni 2020, Nutrients · Source
Bifidobacterium lactis
Strain UABla-12 (UAS Labs)
A friendly gut bacterium used in yogurts and supplements for decades. Our exact strain has its own published human trials, including a 331-person IBS study.
331adults in an IBS trial of our exact strain
4published human trials of our strain
10strains in the Daily Probiotic blend
Why we love it
Bifidobacteria are among the most common bacteria in a healthy adult gut, so we wanted one alongside the lactobacilli in the Daily Probiotic. Our strain, UABla-12, has its own published human trials and has been used in supplements since 2010.
What does the research show?
Digestion
In 331 adults with IBS, our exact strain taken alone for 6 weeks lowered belly pain scores and led to more normal stools than placebo. In a mix with other strains, it helped stool habits settle sooner in 94 adults with constipation.
Children's skin
In 96 toddlers with eczema, our strain given with L. acidophilus DDS-1 and a prebiotic fiber lowered eczema scores by about a third, compared with about a fifth on placebo.
Pregnancy
In 256 pregnant women who also got diet advice, strain BB-12 with L. rhamnosus GG was linked with less gestational diabetes (13% vs 36% on placebo).
Everyday immune health
Strain Bl-04 was linked with a 27% lower risk of colds in 465 active adults. In 225 children, our strain in a two-strain mix was linked with shorter colds (5 days vs 7).
Studies
Human study tested in people Lab study a starting point, not proof
Studies that included our strain (UABla-12)
Eczema scores fell 33.7% vs 19.4% on placebo.
Gerasimov 2010, Am J Clin Dermatol · Source
Colds lasted 5 days vs 7; the share of children who got sick was similar (57% vs 65%).
Gerasimov 2015, Eur J Clin Nutr · Source
Stool habits settled sooner with the mix; overall symptom scores improved in both groups.
Martoni 2019, J Dig Dis · Source
Studies on other strains of this species
Gestational diabetes in 13% vs 36% on placebo.
Luoto 2010, Br J Nutr · Source
27% lower risk of colds than placebo.
West 2014, Clin Nutr · Source
Probiotics shortened gut transit time; HN019 and DN-173 010 had clear effects, BB-12 did not reach significance.
Miller 2016, World J Gastroenterol · Source
Vaginal lactobacilli rose, though not significantly.
Filardo 2024, Nutrients · Source
Which strain do we use?
Our strain is B. lactis UABla-12 (UAS Labs), which has its own human trials, listed first above. Its full scientific name is Bifidobacterium animalis subsp. lactis. The other studies used other strains of this species, and results belong to the strain tested.
Is B. lactis safe to take?
In the trials above, side effects were similar to placebo. Like most strains of this species, UABla-12 carries a natural tetracycline resistance gene; its FDA GRAS safety review judged the gene unlikely to pass to other bacteria. Ask a clinician first if you have a weakened immune system, a central line, a serious illness, or are pregnant or breastfeeding.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Last reviewed: November 2026.
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Reviewed by the Momotaro Apotheca medical team, including OB-GYNs and naturopathic doctors. Educational information, not medical advice. All ingredient research