IBS symptom scores fell by 128 to 157 points, compared with 59 on placebo. Higher dose did better. Well tolerated.
Martoni 2023 · Source
Lactobacillus plantarum
Strain UALp-05 (UAS Labs)
A hardy lactobacillus from fermented foods like sauerkraut, studied in women's health and digestion. A large trial of what is very likely our exact strain looked at people with IBS.
307adults in an IBS trial of what's very likely our strain
Fermentednaturally found in sauerkraut and pickles
10strains in the Daily Probiotic blend
Why we love it
We wanted a sturdy, well-studied lactobacillus that is at home in the gut and has a long history in fermented foods. L. plantarum is one of the most researched species in the probiotic world, and it works alongside the other nine strains in the blend.
What does the research show?
Vaginal yeast
In 93 women with repeat yeast infections, 90 days of oral strain P17630 helped more women reach a healthy lactobacilli flora, with less redness and swelling than placebo. A vaginal capsule of the same strain eased symptoms in 200 women, much like a standard antifungal.
Bacterial vaginosis (BV)
Vaginal tablets that combined L. plantarum with L. brevis CD2 and L. salivarius left all 18 women who used them for 7 days BV-free, compared with 2 of 16 on placebo.
Vaginal pH
In 36 women taking an oral 10-strain capsule that included our strain, UALp-05, vaginal pH dropped slightly over 4 weeks.
Digestion
In 307 adults with diarrhea-type IBS, what is very likely our exact strain lowered symptom scores far more than placebo. Strain 299v eased belly pain in 214 adults with IBS (45% vs 23%).
Colds
Strain HEAL 9, paired with an L. paracasei strain, was linked with fewer colds in 272 healthy adults (55% vs 67% on placebo).
Studies
Human study tested in people Lab study a starting point, not proof
Studies that included our strain (UALp-05)
Vaginal pH dropped slightly (by 0.19 at 4 weeks). Nugent scores and lactobacilli levels did not change significantly.
Martoni 2022 · Source
Studies on other strains of this species
All 18 women on the tablets were BV-free at the end, compared with 2 of 16 on placebo.
Mastromarino 2009 · Source
About 80% of women with BV were cured or improved, compared with 74% on the pH tablet.
Hemalatha 2012 · Source
More women in the probiotic group had healthy lactobacilli flora by day 90; the placebo group did not change. Redness and swelling scores were lower than placebo. Recurrence was not reported.
Vladareanu 2018 · Source
Belly pain severity fell 45%, compared with 23% on placebo.
Ducrotté 2012 · Source
55% caught at least one cold, compared with 67% on placebo.
Berggren 2011 · Source
Symptoms eased in both groups through day 21. No side effects reported.
Bertarello 2024 · Source
Some BV-linked bacteria fell. Lactobacilli rose but not significantly.
Filardo 2024 · Source
Which strain do we use?
Our strain is L. plantarum UALp-05 (UAS Labs), which we believe is the strain published as Lpla33 in the IBS trial above. It was also one of 10 strains in a small oral blend study. The other studies on this page used other strains of this species, and results belong to the strain tested.
Is L. plantarum safe to take?
If you are immunocompromised, have a central line or a heart valve problem, or are critically ill, ask your clinician before taking probiotics. If you are pregnant or breastfeeding, ask your clinician first. Rare heart valve infections with L. plantarum have been reported in people with artificial heart valves. In the 10-strain study, two women had mild cramping or bloating that went away.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Last reviewed: November 2026.
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Reviewed by the Momotaro Apotheca medical team, including OB-GYNs and naturopathic doctors. Educational information, not medical advice. All ingredient research